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Synthetic Biology proposes the adoption of an engineering approach to the redesign of biology. Just as for other engineering disciplines, the adoption a hierarchical approach is likely to result in the formation of a set of specialist roles. The architect is the lead designer in civil engineering, what will the lead designer's role be in Synthetic Biology? By fostering interaction between designers and members of the creative community it is possible to begin to answer this question, to explore the role of design and to consider what tools can be used to enable good biological design.